ESPN analyst: Tigers' rotation seventh-best in baseball

Doug Fister gave the Tigers' rotation a big boost after being acquired at the trade deadline last summer.

Now Fister has the Tigers' rotation ranked among the best in the game, according to an ESPN analyst.

Buster Olney broke down the top rotations in baseball Monday, and had the Tigers seventh.

Of Detroit's staff, Olney wrote:

"Justin Verlander is the reigning AL Cy Young Award winner and Most Valuable Player, yet he didn't even post the best ERA on his own team in the second half of the season. That belonged to Doug Fister, who thrived with Detroit after a midseason trade from Seattle; he had a 2.47 ERA after the All-Star break. Max Scherzer was better than his ERA indicated ? his bad starts were awful, and he had a lot of great starts ? and like Derek Holland, Rick Porcello appeared to learn some stuff about himself in the postseason; remember, Porcello doesn't turn 23 until Tuesday."

The Tigers' rotation was the only one in the AL Central ranked in Olney's top 11.

Here was his order: 1. Phillies, 2. Rays, 3. Angels, 4. Giants, 5. Diamondbacks, 6. Rangers, 7. Tigers, 8. Nationals, 9. Mariners, 10a. Braves, 10b. Dodgers.

Source: http://www.detroitnews.com/article/20111226/SPORTS0104/112260386/1129/rss15

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NCC Announces its Childhood Cancer Research Coalition Program Grant Recipients

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RALEIGH, N.C., Dec. 26, 2011 /PRNewswire-USNewswire/ -- The National Cancer Coalition (NCC) is pleased to announce research grant recipients, which include: Peter C. Adamson, M.D., of Children's Hospital of Philadelphia; Debra L. Friedman, M.D., M.S. of Vanderbilt-Ingram Cancer Center; Thomas W. McLean, M.D. of Wake Forest University School of Medicine; Tobey J. MacDonald, M.D. of Emory University Cancer Center; Edward V. Prochownik, M.D., Ph.D. of Children's Hospital of Pittsburgh; and Alejandro Sweet-Cordero, M.D. of Stanford University Cancer Center.

Through its Childhood Cancer Research Coalition (CCRC) program, the NCC has provided support to help medical centers to better treat their pediatric cancer patients via research funding or access to chemotherapies.? NCC's President Robert Landry stated, "NCC is proud to make these awards and our CCRC program will closely monitor these investigator's impact, as the research translates into advancements in pediatric cancer treatments."?

Dr. Edward Prochownik, Pittsburgh Cancer Institute Professor of Pediatrics and Professor of Microbiology & Molecular Genetics commented, "We greatly appreciate your work on our behalf, especially during these times of shrinking federal funds.? It has increased significantly our ability to maintain cell lines that are essential for our research."? Dr. Tobey MacDonald, Director of Pediatric Neuro-Oncology at the Emory University Cancer Center in Atlanta stated, "Funding such as this by NCC is critical to helping to cultivate innovate ideas and novel concepts. ?We are very grateful for such support."

The cancer research programs supported by the CCRC grants include:?

• Dr. Peter Adamson - pediatric pharmacokinetic studies to determine optimal dosing of anticancer agents.
• Dr. Debra Friedman - long-term academic and social development studies for cancer survivors.
• Dr. Thomas McLean - usefulness of routine imaging for detecting CNS tumor recurrence in children.
• Dr. Tobey MacDonald - investigation study of radiation's effect on the brain.
• Dr. Edward Prochownik - delivery of drug-like molecules to disrupt the functionality of c-Myc to achieve optimal anti-tumor effect.
• Dr. Alejandro Sweet-Cordero - optimal treatment of pediatric bone sarcomas.

The National Cancer Coalition, a 501(c)(3) not-for-profit corporation, supports relief, education, training, and research programs throughout the world. ?The Coalition's medical relief program has provided over $900 million worth of requested specialty pharmaceuticals, essential medicines, and medical technologies to provide access to healthcare facilities that treat underserved patients in 50 countries, including the US.? ?For additional information, please contact NCC at: 919-821-2182 or visit us at: www.nationalcancercoalition.org?

SOURCE National Cancer Coalition

Source: http://c.moreover.com/click/here.pl?r5664792786&f=378

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Community Services - Arts & Craft Class - Day

Arts & Crafts Classes

Monday, Tuesdays, Thursdays and Fridays from 9:30 a.m. to 2:00 p.m.? Choose from a morning class or afternoon class.?

Make beautiful handstitched items, painting, sewing techniques & more?plus lots of fun & fellowship.?

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Video: Enzyme that flips switch on cells' sugar cravings could be anti-cancer target

Video: Enzyme that flips switch on cells' sugar cravings could be anti-cancer target

Thursday, December 22, 2011

Cancer cells tend to take up more glucose than healthy cells, and researchers are increasingly interested in exploiting this tendency with drugs that target cancer cells' altered metabolism.

Cancer cells' sugar cravings arise partly because they turn off their mitochondria, power sources that burn glucose efficiently, in favor of a more inefficient mode of using glucose. They benefit because the byproducts can be used as building blocks for fast-growing cells.

Scientists at Winship Cancer Institute of Emory University have shown that many types of cancer cells flip a switch that diverts glucose away from mitochondria. Their findings suggest that tyrosine kinases, enzymes that drive the growth of several types of cancer, play a greater role in mitochondria than previously recognized.

The results also highlight the enzyme PDHK (pyruvate dehydrogenase kinase) as an important point of control for cancer cell metabolism.

"We and others have shown that PDHK is upregulated in several types of human cancer, and our findings demonstrate a new way that PDHK activity is enhanced in cancer cells," says Jing Chen, PhD, associate professor of hematology and medical oncology at Emory University School of Medicine and Winship Cancer Institute. "PDHK is a very attractive target for anticancer therapy because of its role in regulating cancer metabolism."

Chen and Sumin Kang, PhD, assistant professor of hematology and medical oncology at Emory University School of Medicine, are co-corresponding authors. Postdoctoral fellows Taro Hitosugi, Jun Fan and Tae-Wook Chung are co-first authors of the paper. Co-authors at Emory include Georgia Chen, PhD, Sagar Lonial, MD, Haian Fu, PhD, and Fadlo Khuri, MD. Collaborators at Yale University, Novartis and Cell Signaling Technology contributed to the paper.

Chen and his colleagues started out studying the tyrosine kinase FGFR1, which is activated in several types of cancer. Tyrosine kinases attach a phosphate to other proteins, making them more or less active. They found that FGFR1 activates the enzyme PDHK, which has a gatekeeper function for mitochondria.

"We used FGFR1 as a platform to look at how metabolic enzymes are modified by oncogenic tyrosine kinases," Chen says. "We discovered that several oncogenic tyrosine kinases activate PDHK, and we found that many of those tyrosine kinases are found within mitochondria."

This was a surprise because tyrosine kinases are usually thought to drive growth by being active next to the cell membrane, Chen says.

Introducing a form of PDHK that is insensitive to tyrosine kinases into human cancer cells forces the cells to grow more slowly and form smaller tumors in mice, they found. This indicates that PDHK could be a target for drugs that specifically target cancer cells' altered metabolism.

The experimental drug dichloroacetate (DCA), which inactivates PDHK, is being used in new clinical trials for cancer. Chen is collaborating with Haian Fu, professor of pharmacology and director of the Emory Chemical Biology Discovery Center, to find other, more potent inhibitors of PDHK.

###

The results were published online Thursday by the journal Molecular Cell. http://www.cell.com/molecular-cell/

Emory University: http://www.emory.edu

Thanks to Emory University for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

This press release has been viewed 46 time(s).

Source: http://www.labspaces.net/116285/Video__Enzyme_that_flips_switch_on_cells__sugar_cravings_could_be_anti_cancer_target

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Campaign Finance Law Survives Another Court Challenge

A New York City law that limits campaign contributions from individuals and entities that have business dealings with the city survived another legal challenge on Wednesday, when a federal appeals panel ruled that the law did not violate the free-speech and equal-protection provisions of the United States Constitution.

Several plaintiffs had challenged the city?s ?pay to play? regulations in a lawsuit filed in federal court in Manhattan in 2008. A district court judge upheld the constitutionality of the law in February 2009.

The plaintiffs, including former Councilman Tom Ognibene and the State Conservative Party, appealed that ruling, but their legal challenge has now been rejected by the United States Court of Appeals for the Second Circuit.

In 1988, after a wave of local scandals, the City Council passed the Campaign Finance Act, which established public financing for citywide offices, the five offices of borough president and the 52 offices of the City Council. The law also limited individual donor contributions.

In 2006, the Campaign Finance Board reported that, despite the law, more than 20 percent of contributions in the 2001 and 2005 election cycles were from individuals and entities doing business with the city, making up only 5 percent of contributors, and that large donations were more likely to come from such donors than small ones.

Later amendments to the law reduced by 90 percent the amount that those with business before the city were allowed to contribute to a candidate; excluded their contributions from matching public money; and expanded the prohibition on corporate contributions to include partnerships, limited liability corporations and limited liability partnerships.

This week?s ruling keeps those provisions in place. The city?s Law Department litigated the case for the city.

?This is a significant victory for individual New Yorkers, clean government and clean campaign finance,? Christine C. Quinn, the speaker of the City Council and a driving force behind the original passage of the provisions, said in a statement. ?Powerful forces that didn?t want big business and special interests taken out of campaign donations failed to overturn our law.?

?New York City?s limits on pay-to-play are among the most comprehensive of any jurisdiction in the county,? Amy Loprest, executive director of the city?s Campaign Finance Board, said in a statement. ?It is making a difference in fighting corruption, both real and perceived.?

Source: http://cityroom.blogs.nytimes.com/2011/12/22/citys-limits-on-pay-to-play-by-campaign-donors-survive-lawsuit/

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BP: Rig partner liable for own punitive damages

BP wants to shield itself from having to compensate Halliburton for punitive damages, fines and penalties the cement contractor may face for its role in the deadly 2010 rig explosion and oil spill in the Gulf of Mexico.

Billions of dollars are potentially at stake as a federal trial scheduled for February approaches. The civil trial, which is expected to last eight weeks, is being held to assign shares of fault to the companies involved in the worst offshore oil spill in U.S. history. It also was to determine whether rig owner Transocean can limit what it pays those making claims under maritime law.

London-based BP PLC said in court papers Wednesday the law and its contract with Halliburton don't permit BP to be held responsible for covering punitive damages ultimately faced by Halliburton, which is based in Houston.

The explosion off Louisiana killed 11 rig workers and led to more than 200 million gallons (757 million liters) of oil spewing from a well a mile (two kilometers) beneath the sea, according to government estimates. BP owned the well and was leasing the Deepwater Horizon rig from Swiss-based Transocean Ltd.

BP also said the court should deny Halliburton's request that BP indemnify Halliburton for other costs it has incurred related to the spill. It said the request is premature since the trial hasn't started.

BP has spent considerable legal firepower trying to deflect blame for the disaster.

It has already spent or committed tens of billions of dollars on cleaning up the Gulf and compensating fishermen, condo owners, restaurants and other businesses and individuals harmed by the oil spill. However, that sum could pale in comparison to what it faces depending on court rulings, the outcome of the trial and any fines and penalties ultimately imposed by government agencies.

BP claims every single safety system and device and well control procedure on the Deepwater Horizon rig failed.

BP also has accused Halliburton of fraud for allegedly concealing critical information about cement tests it conducted. An oil well must be cemented properly to avoid blowouts.

BP has argued that a botched cement job led to the Macondo well blowout.

Halliburton, Transocean and other companies involved in the disaster have made counterclaims against BP.

A report issued in September by the U.S. Coast Guard and the agency that regulates offshore drilling concluded that BP bears ultimate responsibility for the disaster. BP has asked the court to keep that report out of the civil trial.

___

Follow Harry R. Weber at http://www.facebook.com/HarryRWeberAP

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/f70471f764144b2fab526d39972d37b3/Article_2011-12-21-Gulf%20Oil%20Spill/id-1ff1b74cd3c944cbbeac42eb974e011e

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PudgyOne replied to Install Dell AIO 962 on Windows 7 64B German in Printers Forum .

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Source: http://en.community.dell.com/support-forums/peripherals/default.aspx?ActivityMessageId=3fdfe269-f667-46b2-a949-bedb41c8f914

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US gray wolves rebound but face uncertain future (AP)

ATLANTA, Mich. ? After devoting four decades and tens of millions of dollars to saving the gray wolf, the federal government wants to get out of the wolf-protection business, leaving it to individual states ? and the wolves themselves ? to determine the future of the legendary predator.

The Obama administration Wednesday declared more than 4,000 wolves in Michigan, Minnesota and Wisconsin have recovered from widespread extermination and will be removed from the endangered species list.

"Gray wolves are thriving in the Great Lakes region," said Dan Ashe, director of the U.S. Fish and Wildlife Service.

Coupled with an earlier move that lifted protections in five western states, the decision puts the gray wolf at a historical crossroads ? one that could test both its reputation for resilience and the tolerance of ranchers and hunters who bemoan its attacks on livestock and big game.

Wolves have returned only to isolated pockets of the territory they once occupied, and increasing numbers are dying at the hands of hunters, wildlife agents and ranchers. Now, the legal shield making it a crime to gun them down is being lifted in the only two sections of the lower 48 states where significant numbers exist.

State officials said they will keep wolf numbers healthy, but all three western Great Lakes states will allow wolves to be shot if they are caught assaulting farm animals or pets.

"We now have the ability to kill a wolf that needs killing," said Russ Mason, Michigan's wildlife division chief.

Hunting and trapping also could be allowed. No seasons have been set.

Some environmentalists supported the decision. Others whose lawsuits blocked previous efforts to drop Great Lakes wolves from the endangered list said they were disappointed but had not decided whether to return to court.

"We believe the wolf has not recovered," said Howard Goldman, Minnesota state director for the Humane Society of the United States.

Since being declared endangered in 1974, the American wolf population has grown fivefold ? to about 6,200 animals wandering parts of 10 states outside Alaska.

"They are in the best position they've been in for the past 100 years," said David Mech, a senior scientist with the U.S. Geological Survey in St. Paul, Minn., and a leading wolf expert. The animals' long-term survival will "depend on how much wild land remains available, because wolves are not compatible with areas that are agricultural and have a lot of humans. There's just too much conflict."

Also Wednesday, the government put off a decision on protections in 29 Eastern states that presently have no wolves. The Interior Department said it still was reconsidering its prior claim that wolves in those states historically were a separate species, which effectively would cancel out protections now in place.

Gray wolves in Wyoming are next in line to come off the endangered list, which is expected sometime next year. Similar actions are planned for most remaining western states and the Great Plains.

Since 1991, the federal government has spent $92.6 million on gray wolf recovery programs and state agencies have chipped in $13.9 million, according to documents reviewed by The Associated Press.

"We are ready to declare success in those areas where wolves are now secure, turn over management responsibility to the states and begin to focus our limited resources on other species that are in trouble," said Gary Frazer, assistant director for the Fish and Wildlife Service's endangered species program.

The government plans to continue trying to bolster a struggling Mexican gray wolf population in the desert Southwest and is weighing whether to expand protections for small numbers of the animals that have slipped into the Pacific Northwest from Canada.

But there are no plans to promote their return elsewhere. Federal officials say it's not the government's job to return wolves to their previous range as long as the population is stable.

In Montana and Idaho, where wolves can be legally hunted and trapped, officials want to drive down wolf numbers this winter to curb attacks on farm animals and elk.

Some scientists and advocates say the hunts show what will happen when federal safeguards are lifted elsewhere. The government, they say, is abandoning the recovery effort too soon, before packs can take hold in new areas. Vast, wild territories in the southern Rockies and Northeast are ripe for wolves but unoccupied.

"The habitat is there. The prey is there. Why not give them the chance?" said Chris Amato, New York's assistant commissioner for natural resources.

But federal officials are grappling with tight budgets and political pressure to expand hunting and prevent wolves from invading new turf. They insist the animals known for their eerie howl, graceful lope and ruthless efficiency in slaughtering prey will get by on their own with help from state agencies.

North America was once home to as many as 2 million gray wolves. By the 1930s, fur traders, bounty hunters and government agents had poisoned, trapped and shot almost all wolves outside Canada and Alaska.

The surviving 1,200 were clustered in northern Minnesota in the 1970s. With endangered species protection, their numbers rocketed to nearly 3,000 in the state and they gradually spread elsewhere.

Today, Wisconsin has about 782 wolves and Michigan 687 ? far above what biologists said were needed for sustainable populations.

The success story is hardly surprising in woodlands teeming with deer, said John Vucetich, a biologist at Michigan Tech University. But even in such an ideal setting, the wolves could return only when killing them became illegal.

"What do wolves need to survive?" Vucetich said. "They need forest cover, and they need prey. And they need not to be shot."

Shooting already is happening ? legally or not ? as adventurous wolves range into new regions such as Michigan's Lower Peninsula and the plains of eastern Montana.

Those sightings are unsettling to farmers because resurgent packs have killed thousands of livestock. Some owners may quietly take matters into their own hands ? "shoot, shovel and shut up," said Jim Baker, who raises 60 beef cattle near the village of Atlanta, Mich.

Wolves "could wipe me out in a couple of nights if they wanted," Baker said.

Since the late 1980s, more than 5,000 wolves have been killed legally, according to an AP review of state and federal records. Hundreds more have been killed illegally over the past two decades in the Northern Rockies alone.

Ranchers in some areas are allowed under federal law to shoot wolves to defend their livestock. In the northern Rockies, government wildlife agents have routinely shot wolves from aircraft in response to such attacks. Often that involves trapping a single wolf, fitting it with a radio collar and tracking it back to its den so the entire pack can be killed.

Biologists are confident that neither legal hunts nor poaching will push wolves back to the brink of extinction.

Idaho has been the most aggressive in reducing wolf numbers, offering a 10-month hunting season that sets no limits. State officials say they intend to reduce the population from 750 to as few as 150 ? the minimum the federal government says is needed in each Northern Rockies state to keep the animal off the endangered list.

Studies indicate plentiful habitat remains in other regions, including upstate New York, northern New England and the southern Rockies of Colorado and Utah. But experts say the Fish and Wildlife Service's plan would mean that any wolves wandering into those states could be shot on sight unless protected by state laws.

"Wolves, next to people, are one of the most adaptable animals in the world," said Ed Bangs, a former Fish and Wildlife Service biologist who led the effort to return wolves to the northern Rockies. "The key with wolves is, it's all about human tolerance."

___

Brown reported from Billings, Mont.

Source: http://us.rd.yahoo.com/dailynews/rss/environment/*http%3A//news.yahoo.com/s/ap/20111221/ap_on_re_us/us_gray_wolf_future

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Adam Lambert's Trespassing To Drop In March

The delayed For Your Entertainment follow-up sees Lambert working with the likes of Dr. Luke and Bruno Mars.
By James Montgomery

Adam Lambert
Photo: Kevork Djansezian/ Getty Images

He's already referred to it as his "dream" album and as "existential pop," but now we know what Adam Lambert will actually be calling his sophomore album: Trespassing.

That's according to a press release sent out by his label, RCA, which not only announced the title of Lambert's follow-up to For Your Entertainment but revealed that the much-delayed disc would finally be hitting stores on March 20. The news came one day after Lambert unveiled a snippet of the album's first single, "Better Than I Know Myself."

Lambert serves as executive producer on the new album, which he describes as "an exciting journey through the past two years of my life. It's been a transformative period and I really wanted to make music from what I've experienced. All these songs honestly explore the ups and downs of my reality."

He also co-wrote most of the record, collaborating with a (seriously) loaded roster of talented hitmakers that includes Dr. Luke, Bruno Mars, Pharrell Williams, Benny Blanco, Nile Rodgers and Claude Kelly.

And while his Glamberts will still have to wait until March to hear Trespassing, the simple fact that there's an actual release date for the album is probably good enough for now, given that for months it looked like the album might not come out at all. In November, Lambert spoke to The Advocate about the delays that had beset the project, which included some, uh, issues with RCA and a whole lot of tinkering to make his new songs right.

"I don't know how other artists do it, but for this project, I'm adopting the mentality of 'just keep writing and keep recording as much as possible,' " he said. "And then when we know that we're ready to decide which tracks are going to be on the album, we'll look at everything and narrow it down."

Related Artists

• Adam Lambert

Source: http://www.mtv.com/news/articles/1676118/adam-lambert-trespassing.jhtml

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The lunatic is in my head (Balloon Juice)

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Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/175982598?client_source=feed&format=rss

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The story behind John Cena's salute

Every night before he enters the ring, John Cena, clad in camouflage shorts, stands at attention and salutes as though a commanding officer were standing in front of him barking orders. Most think that Cena is simply acknowledging his devoted fans, which the leader of the Cenation will not deny.

?It?s a salute of loyalty to those that stand by me, that have been doing it for years,? Cena explained to WWE.com.

However, for the 10-time WWE Champion, there is also a much deeper meaning behind his gestures.

?Every night when I do that salute, it?s also a sign of respect to the men and women that don the uniform of the Armed Forces,? he declared.

John Cena holds the Armed Forces in the highest esteem and has implemented many aspects of the military way into his attitude. It goes beyond camo shorts and a salute.

?When it came my time to slowly redefine who I was from wrestler to hip hop thug, to the next step in my career, I basically took the ideologies of discipline from the Armed Forces,? Cena said. ?I took honor, code and country and came up with hustle, loyalty and respect. I think exactly like they do.?

The leader of the Cenation also has one very personal ritual related to the Armed Forces. Those who pay close attention to Cena right before a match begins will see him remove a pair of dog tags from around his neck and kiss them before handing them to the referee or ringside attendant for safe keeping. But the Superstar prefers to keep the meaning behind the tags to himself.

?That?s secret information that I?ve told a few Make-A-Wish families and those people who need to know. [WWE.com] doesn?t need to know,? Cena lightheartedly explained.

As evidenced by his passionate speech at Fort Bragg during Tribute to the Troops, John Cena is extremely reverent toward the men and women of the United States Armed Forces and will continue to do whatever he can to honor their ultimate sacrifice.

Source: http://www.wwe.com/shows/tributetothetroops/story-behind-cena-salute

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The Common Sense in Energy Investing

I can't help but feel sorry for them.

Walking through an office full of traders last week, it was difficult not to.

You see, these guys have been living on coffee and cigarettes for months, their eyes glued to flashing computer screens...

It's all part of the countless buying and selling they do on a daily basis.

Before I reached the end of the hallway, I heard them whispering amongst themselves. It seemed half of their hush-hush conversations concerned Europe; the rest, Obama.

I caught sight of one poor soul holding an argument with himself. Whichever side was winning wasn't clear, but his feverish pace was taking a grim toll.

?I'm getting killed out there,? he murmured as I peeked around the corner of his unadorned cubicle.

You might be asking yourself why I am so sympathetic to the professional trader's plight.

Well, for all their maneuvers in the market, these people don't hold an ounce of sense when it comes to investing. And I know for a fact that these "professional traders" are losing even more to another group of investors...

Us.

Guaranteed Energy Growth

If I'd had the chance, I'd have given the gentleman debating with himself just one bit of advice: Energy stocks are ripe for the picking.

It's obvious how skewed the global oil industry is today. To think otherwise would be foolish.

Within a matter of five decades, we've seen National Oil Companies gain control of nearly 95% of the world's oil reserves. OPEC members alone are responsible for one-third of global supply.

What many people don't realize is how distorted things are on the other side of the equation.

The ten largest oil-consuming countries in the world today make up 60% of total demand.

Ten countries!

Just take the top five of that list, and we're talking about 40%.

That means half of the world's oil demand ? now approaching 90 million barrels per day ? comes from a handful of countries...

click to enlarge image

Did you happen to notice the light blue slice of the pie?

Within just 15 years, China's oil demand has more than doubled.

Several weeks ago, the IEA reported 90% of the growth in global energy demand will come from non-OECD countries.

By 2035, China will account for more than 30% of the world's energy. China's demand for oil last month was the second-highest on record.

Although it won't be enough to overtake the United States' top spot, finding that energy will be a daunting task...

Of course, the Middle Kingdom is already making preparations?? which is why Chinese companies have been scouring North America for a solution, spending billions in the process. And it's no secret as to which energy sources will be dominating the scene by then.

Our analysts have traveled the world over, dedicated to finding the best and most profitable investments in the global energy markets. All you have to do to join our Energy and Capital investment community is sign up for the newsletter below. You'll also get our free report, Natural Gas Price Forecast by our resident expert Keith Kohl.

What's the cost behind this inevitable growth??1.5 trillion dollars every year from now until 2035.

According to the IEA, that's how much the world will need to invest in the energy-supply infrastructure.

So you can understand why we're looking to do more than just scrape by with day-to-day trading...

Look, no matter what you do, you'll never be able to control the daily flow of news coming from Europe, or know exactly how the geopolitical game of Risk will turn out in the Middle East.

You can, however, practically guarantee your energy profits.

How?

It's a theme we've touched on all year:

You can either roll the dice with the bigger names in the field, all of which are being squeezed out of the world's oil fields by those domineering NOCs, or you can do exactly what the big players are doing ? that is, you can find the sorely undervalued players that are being scooped up feverishly.

Take a look at the following chart:

Ever since my report alerted readers to the huge potential in the U.S. oil sector, plays like this one have more than doubled.

The best part?

This is only one example of how profitable these plays are right now, all during a market that's tearing professional traders (like the ones I mentioned earlier) apart on a daily basis.

That's why I've been beating this drum for years ? and will continue to do so.

To get complete articles and information, join our newsletter for FREE!

Daily commentary and advice from energy investment experts
Access to some of the best oil, gas, and cleantech stock picks around
Foresight on how the future of energy will unfold

Until next time,

Keith Kohl

@KeithKohl1 on Twitter

A true insider in the energy markets, Keith is one of few financial reporters to have visited the Alberta tar sands. His research has helped thousands of investors capitalize from the rapidly changing face of energy. Keith connects with hundreds of thousands of readers as the Managing Editor of Energy & Capital as well as Investment Director of Angel Publishing's Energy Investor. For years, Keith has been providing in-depth coverage of the Bakken, the Haynesville Shale, and the Marcellus natural gas formations ? all ahead of the mainstream media. For more on Keith, go to his editor's page.

Media / Interview Requests? Click Here.

Source: http://www.energyandcapital.com/articles/the-common-sense-in-energy-investing/1975

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Video: Joe Jonas and Community Cast stop by The Soup!

Don?t forget to watch an all new?The Soup?tonight at 10pm! Watch Joel?s imagination run wild as he dreams up all sorts of crazy characters ? including his entire?Community?cast. Then, see all the SOUPER fun you can have on the go with the show?s new?iPhone app?commercial, featuring?Joe Jonas!   THE SOUP Wednesdays at 10pm EST on [...]

Source: http://www.celebritymound.com/video-joe-jonas-and-community-cast-stop-by-the-soup/?utm_source=rss&utm_medium=rss&utm_campaign=video-joe-jonas-and-community-cast-stop-by-the-soup

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Obama visiting Fort Bragg to mark end of Iraq war (AP)

WASHINGTON ? President Barack Obama is marking the end of the Iraq war with a tribute to the troops who fought and died in a conflict he opposed from the start.

Accompanied by first lady Michelle Obama, the president was traveling Wednesday to Fort Bragg in North Carolina to address service members and their families as he brings the war to a close.

At a base that's seen more than 200 deaths over nearly nine years of fighting in Iraq, Obama was to highlight the human side of the war, reflecting on the bravery and sacrifices of U.S. forces now on their way back home.

All U.S. troops are to be out of Iraq Dec. 31, though Obama has pledged the U.S. will continue to help Iraq as it faces an uncertain future in a volatile region of the world. Even as majorities in the U.S. public favor ending the war, some Republicans have criticized Obama's withdrawal, arguing he's leaving behind an unstable Iraq that could hurt U.S. interests and fall subject to influence from neighboring Iran.

Obama has on several occasions addressed his reasons for ending the war, casting it as a promise kept after he ran for president as an anti-war candidate and speaking of the need to refocus U.S. attention on rebuilding the troubled economy at home.

On Wednesday, his focus will be principally on the troops and their role and his commitment to ensuring veterans get the jobs and resources they need once they're back home. His audience will be those people most personally affected, including troops back from Iraq and their families.

In a local television interview Tuesday, Obama previewed some of his likely themes.

"We must not forget the men and women who gave their lives, tens of thousands wounded, all those missed birthday parties, missed soccer games and missed dinners because folks were on their second or third deployment. We should not take that for granted," the president told KOAA-TV in Colorado Springs, Colo. "It is an extraordinary testimony to the bravery, courage, dedication and patriotism of our soldiers."

It's the president's first visit to Fort Bragg, which is home to Army Special Operations, the 18th Airborne Corps and the 82nd Airborne, among others. Special Forces troops from Fort Bragg were among the first soldiers in Iraq during the 2003 invasion and its paratroopers helped lead the 2007 troop increase.

North Carolina, which Obama narrowly won in 2008, also is an important state for the 2012 presidential election and will host the Democratic convention.

___

Associated Press writer Martha Waggoner in Raleigh, N.C., contributed to this report.

Source: http://us.rd.yahoo.com/dailynews/rss/us/*http%3A//news.yahoo.com/s/ap/20111214/ap_on_go_pr_wh/us_obama

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'A new chapter': US shuts down Iraq war

NBC News

U.S. troops take part in the end of mission ceremony in Baghdad, Iraq, on Thursday

By msnbc.com staff and news services

Updated at 6:43 a.m. ET

BAGHDAD -- Secretary of Defense Leon Panetta marked the end of the U.S. war in Iraq?at a highly symbolic ceremony Thursday.

U.S. soldiers rolled up the flag for American forces in Iraq and slipped it into a camouflage-colored sleeve, formally "casing" it, according to Army tradition.

Panetta said veterans of the nearly nine-year conflict can be "secure in knowing that your sacrifice has helped the Iraqi people to cast tyranny aside."

Iraqi Prime Minister Nouri al-Maliki and President Jalal Talabani were invited to the ceremony but did?not attend.

---

Nearly 4,500 U.S. soldiers and tens of thousands of Iraqis lost their lives in a war that began with a "Shock and Awe" campaign of missiles pounding Baghdad, but later descended into a bloody sectarian struggle between long-oppressed majority Shiites and their former Sunni masters.

"After a lot of blood spilled by Iraqis and Americans, the mission of an Iraq that could govern and secure itself has become real," Panetta added.

Gen. Lloyd Austin, the top U.S. commander in Iraq, and Army Gen. Martin Dempsey, the chairman of the Joint Chiefs of Staff, also?spoke?during the ceremony?at Baghdad International Airport.

Updated at 5:46 a.m. ET:?Austin says Iraqis now?have "unprecedented opportunities."

Updated at 5:42 a.m ET: "Since 2003, we have helped the Iraqi security forces grow from zero to 650,000-strong," Austin says.

Updated at 5:40 a.m. ET: Austin recalls how he was present when American?forces secured the airfield where?the ceremony is being held.?"After 21 days of tough fighting, we ended Saddam Hussein's reign of terror,"?he adds.

Updated at 5:37 a.m. ET: Army Gen. Martin Dempsey, the chairman of the Joint Chiefs of Staff, points out that the next time he visits?Baghdad it will have to?be at the invitation of the Iraqi?government. "I kinda like that," he adds.

Updated at 5:32 a.m. ET: "This is not the end, this is the beginning," Panetta says.?"May God bless Iraq, its people and its future."

Saddam's Iraq is gone, but in its place is a state with close ties to one of America's biggest and most unpredictable enemies: Iran. NBC's Richard Engel has been covering the war from the start, and went back for this historic week to take a closer look at the Iran connection.

Updated at 5:29 a.m. ET: "Let me be clear, Iraq will be tested in the days ahead -- by terrorism, by those who would seek to divide," Panetta says. "Challenges remain but the United States will be there to stand with the Iraqi people. We are not about to turn our backs on all that has been sacrificed and accomplished."

Updated at 5:26 a.m. ET: "Your sacrifice has helped the Iraqi people begin a new chapter in history, free from tyranny," Panetta says.?"This outcome was never certain, particularly during the war's darkest days."

Updated at 5:23 a.m. ET: Panetta highlights the "heartbreak" of military families who?watched their loved ones go off to war.

Updated at 5:18 a.m. ET: "It is a profound honor to be here in Baghdad," Panetta says at ceremony."No words, no ceremony can provide full tribute to the sacrifices that have brought this day to pass."

Updated at 5:16 a.m. ET: "We look forward to an Iraq that is sovereign, secure and self-reliant," US Ambassador to Iraq James Jeffrey says.

Read more about the?Iraq withdrawal

Published at 4:45 a.m. ET: After nearly nine years, 4,500 American dead, 32,000 wounded and more than $800 billion, U.S. officials prepared Thursday to formally shut down the war in Iraq ? a conflict that U.S. Defense Secretary Leon Panetta said was worth the price in blood and money, as it set Iraq on a path to democracy.

Panetta stepped off his military plane in Baghdad Thursday as the leader of America's war in Iraq, but will leave as one of many top U.S. and global officials who hope to work with the struggling nation as it tries to find its new place in the Middle East and the broader world.

He and several other U.S. diplomatic, military and defense leaders will participate in a highly symbolic ceremony during which the flag of U.S. Forces-Iraq will officially be retired, or "cased," according to Army tradition.

During several stops in Afghanistan this week, Panetta made it clear that the U.S. can be proud of its accomplishments in Iraq, and that the cost of the bitterly divisive war was worth it.

After nearly nine years and 4,500 American lives lost, President Obama and the first lady officially marked the end of the Iraq war Wednesday. NBC's Kristen Welker has more.

"We spilled a lot of blood there," Panetta said. "But all of that has not been in vain. It's been to achieve a mission making that country sovereign and independent and able to govern and secure itself."

That, he said, is "a tribute to everybody ? everybody who fought in that war, everybody who spilled blood in that war, everybody who was dedicated to making sure we could achieve that mission."

Panetta has echoed President Barack Obama's promise that the U.S. plans to keep a robust diplomatic presence in Iraq, foster a deep and lasting relationship with the nation and maintain a strong military force in the region.

Raging sectarianism
As of Thursday, there were two U.S. bases and about 4,000 U.S. troops in Iraq ? a dramatic drop from the roughly 500 military installations and as many as 170,000 troops during the surge ordered by President George W. Bush in 2007, when violence and raging sectarianism gripped the country. All U.S. troops are slated to be out of Iraq by the end of the year, but officials are likely to meet that goal a bit before then.

The total U.S. departure is a bit earlier than initially planned, and military leaders worry that it is premature for the still maturing Iraqi security forces, who face continuing struggles to develop the logistics, air operations, surveillance and intelligence sharing capabilities they will need in what has long been a difficult neighborhood.

U.S. officials were unable to reach an agreement with the Iraqis on legal issues and troop immunity that would have allowed a small training and counterterrorism force to remain. U.S. defense officials said they expect there will be no movement on that issue until sometime next year.

Jon Soltz of VoteVets.org and Matthew Hoh of the Center for International Policy debate the winners and losers of the Iraq War and the non-military presence that will remain.

Still, despite Obama's earlier contention that all American troops would be home for Christmas, at least 4,000 forces will remain in Kuwait for some months. The troops will be able to help finalize the move out of Iraq, but could also be used as a quick reaction force if needed.

Bombings and attacks have eased since American and Iraqi security forces weakened insurgents. But roadside bombs, car bombs and assassinations still kill and maim almost every day.

A frail economy, constant power shortages, scarce jobs and discontent with political leaders all fuel uncertainty among Iraqis.

"Thanks to the Americans. They took us away from Saddam Hussein, I have to say that. But I think now we are going to be in trouble," said Malik Abed, 44, a vendor at a Baghdad fish market. "Maybe the terrorists will start attacking us again."

Read more content from msnbc.com and NBC News:

The Associated Press and Reuters contributed to this report.

Source: http://worldnews.msnbc.msn.com/_news/2011/12/15/9461909-a-new-chapter-us-shuts-down-iraq-war

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Virginia Tech biomedical program receives 2 of Toyota's research safety projects

Public release date: 6-Dec-2011
[ | E-mail | Share ]

Contact: Lynn Nystrom
tansy@vt.edu
540-231-4371
Virginia Tech

Brain trauma research honored

Of four new research projects announced today (Dec. 6) by Toyota's Collaborative Safety Research Center, two include the Virginia Tech Wake Forest University School of Biomedical Engineering and Sciences. And just a few days ago, the Brain Trauma Foundation honored the Virginia Tech Wake Forest University biomedical program with its 2011 Brain Trauma Foundation Award. Toyota funded some of the research that led to this award.

"We are confident our research advancements will help reduce the risk of traumatic brain injuries in both automobile impacts as well as on the football field," said Stefan Duma, professor and head of the biomedical engineering program for Virginia Tech and Wake Forest University. "We are grateful to Toyota for its support of this important, lifesaving research and to the Brain Trauma Foundation for its recognition."

Toyota launched its research safety center in January 2011 with an initial investment of $50 million. This center pursues automotive safety research through a collaborative model that prioritizes sharing Toyota's talent and technology with a broad range of institutions, and Virginia Tech's biomedical program continues to receive significant support.

At Virginia Tech, one of the new Toyota projects will focus on abdominal injuries. Duma said this study will look at the relationship between age and abdominal injuries caused by automobile crashes in the United States, to determine if a specific population, such as senior drivers, is more vulnerable to abdominal injuries during these events.

The second project involving Virginia Tech is a partnership with George Washington University. Duma explained the project will upgrade a frontal impact test dummy, initially developed by the National Highway Safety Transportation Safety Administration, that allows automotive manufacturers an advanced tool to assess the injury risk of drivers and passengers in vehicles using crash tests. The dummy, named THOR, may lead to new technologies for the design of vehicles and their restraint systems.

Virginia Tech's biomedical program has a history of work in crash mechanics. Over the past three years, the U.S. Army awarded Duma and his colleagues Warren Hardy and Clay Gabler, also biomedical engineering faculty members, over $10 million in research awards to study the biomechanics of head, neck, and chest injury.

In 2008, a group of nine international car manufacturers and suppliers awarded $4.9 million to the Virginia Tech Wake Forest University School of Biomedical Engineering and Science's Center for Injury Biomechanics, to conduct a study to produce a better understanding of what happens to individuals subjected to body trauma.

"Today's announcements cap a successful first year for Toyota's Collaborate Safety Research Center and our efforts to act as a catalyst for the advancement of automotive safety for the entire industry. We look forward to further expanding our talent-sharing research model and helping advance the development of safety technologies that can benefit all of society," said Chuck Gulash, senior executive engineer at the Toyota Technical Center and the safety research center director.

Of the remaining two projects, one is with the University of Iowa to study driver behavior related to foot placement. The hope is to better quantify and predict driver-vehicle interactions to aid in the development of vehicle-based enhancements. The second one collaborates with the University of Virginia to study of the capabilities of Toyota's THUMS modeling system in capturing the effects of complex automobile crash scenarios at the "whole body" level.

Crash modeling technologies help researchers analyze millions of data points to better understand the mechanisms that cause injuries in car crashes, which helps inform the development of new safety technologies for airbags, seatbelt systems and vehicle body structures.

Since the CSRC was first launched, Toyota has announced 17 research projects with 12 institutions. In keeping with its open model, the safety center intends to publish as much of this research as possible to make it available to federal agencies, the industry and academia.

###

---

[ | E-mail | Share ]

?

AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Public release date: 6-Dec-2011
[ | E-mail | Share ]

Contact: Lynn Nystrom
tansy@vt.edu
540-231-4371
Virginia Tech

Brain trauma research honored

Of four new research projects announced today (Dec. 6) by Toyota's Collaborative Safety Research Center, two include the Virginia Tech Wake Forest University School of Biomedical Engineering and Sciences. And just a few days ago, the Brain Trauma Foundation honored the Virginia Tech Wake Forest University biomedical program with its 2011 Brain Trauma Foundation Award. Toyota funded some of the research that led to this award.

"We are confident our research advancements will help reduce the risk of traumatic brain injuries in both automobile impacts as well as on the football field," said Stefan Duma, professor and head of the biomedical engineering program for Virginia Tech and Wake Forest University. "We are grateful to Toyota for its support of this important, lifesaving research and to the Brain Trauma Foundation for its recognition."

Toyota launched its research safety center in January 2011 with an initial investment of $50 million. This center pursues automotive safety research through a collaborative model that prioritizes sharing Toyota's talent and technology with a broad range of institutions, and Virginia Tech's biomedical program continues to receive significant support.

At Virginia Tech, one of the new Toyota projects will focus on abdominal injuries. Duma said this study will look at the relationship between age and abdominal injuries caused by automobile crashes in the United States, to determine if a specific population, such as senior drivers, is more vulnerable to abdominal injuries during these events.

The second project involving Virginia Tech is a partnership with George Washington University. Duma explained the project will upgrade a frontal impact test dummy, initially developed by the National Highway Safety Transportation Safety Administration, that allows automotive manufacturers an advanced tool to assess the injury risk of drivers and passengers in vehicles using crash tests. The dummy, named THOR, may lead to new technologies for the design of vehicles and their restraint systems.

Virginia Tech's biomedical program has a history of work in crash mechanics. Over the past three years, the U.S. Army awarded Duma and his colleagues Warren Hardy and Clay Gabler, also biomedical engineering faculty members, over $10 million in research awards to study the biomechanics of head, neck, and chest injury.

In 2008, a group of nine international car manufacturers and suppliers awarded $4.9 million to the Virginia Tech Wake Forest University School of Biomedical Engineering and Science's Center for Injury Biomechanics, to conduct a study to produce a better understanding of what happens to individuals subjected to body trauma.

"Today's announcements cap a successful first year for Toyota's Collaborate Safety Research Center and our efforts to act as a catalyst for the advancement of automotive safety for the entire industry. We look forward to further expanding our talent-sharing research model and helping advance the development of safety technologies that can benefit all of society," said Chuck Gulash, senior executive engineer at the Toyota Technical Center and the safety research center director.

Of the remaining two projects, one is with the University of Iowa to study driver behavior related to foot placement. The hope is to better quantify and predict driver-vehicle interactions to aid in the development of vehicle-based enhancements. The second one collaborates with the University of Virginia to study of the capabilities of Toyota's THUMS modeling system in capturing the effects of complex automobile crash scenarios at the "whole body" level.

Crash modeling technologies help researchers analyze millions of data points to better understand the mechanisms that cause injuries in car crashes, which helps inform the development of new safety technologies for airbags, seatbelt systems and vehicle body structures.

Since the CSRC was first launched, Toyota has announced 17 research projects with 12 institutions. In keeping with its open model, the safety center intends to publish as much of this research as possible to make it available to federal agencies, the industry and academia.

###

---

[ | E-mail | Share ]

?

AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Source: http://www.eurekalert.org/pub_releases/2011-12/vt-vtb120111.php

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Elden Hughes dies at 80; longtime Sierra Club leader

Elden Hughes, a crusader for wild places and a leader of the Sierra Club's battles to protect desert wilderness from development and abuse, has died. He was 80.

Hughes, who died of prostate cancer early Sunday at his home in Joshua Tree, Calif., was a visionary and inspirational figure who mentored generations of activists in fights to reduce the environmental damage of developments, including renewable energy projects on pristine landscapes and wildlife.

Hughes was among a dozen environmentalists invited to the White House in 1994 when President Clinton signed the landmark California Desert Protection Act, which created a new national park in the eastern Mojave Desert and elevated Death Valley and Joshua Tree from national monument to national park status.

---

FOR THE RECORD: An earlier version of this online article misstated the size of a land purchase that Elden Hughes helped the Wildlands Conservancy complete in 2003 as more than 62,000 acres. The conservancy purchased more than 620,000 acres.

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The Sierra Club stalwart with gray hair and piercing blue eyes was accompanied by a dozen baby California desert tortoises he had used as calling cards to lobby hundreds of congressmen and senators.

"Elden and his wife, Patty, would walk into a congressional office and place those little critters down on a table," recalled fellow Sierra Club activist Jim Dodson. "Within seconds, staffers would be oohing and cooing over tortoises big as silver dollars and cute as buttons. Next thing you know, the boss would wander out of a back office wanting to know what the hubbub was about. It was hard to say no to Elden after that."

Sen. Dianne Feinstein (D-Calif.), author of the final version of the protection act, said, "Hughes dedicated his life to the protection and revival of our great Mojave Desert and its tortoises. I'll never forget when he brought a couple of tortoises to a large constituent breakfast and the amazed and glowing faces of youngsters when he told them they live for decades. Elden led a huge citizen effort in 1993 to support my Desert Protection Act. We will pass the second Desert Protection Act, now pending in committee, in his honor. He will be greatly missed."

In 2003, Hughes helped the Wildlands Conservancy, a private nonprofit environmental group, complete a massive land-buying program. More than 620,000 acres of former railroad parcels from the Salton Sea to the Colorado River purchased with $45 million in private donations collected by the conservancy and $18 million in federal funds were handed over to the public for preservation.

In an interview at the time, Hughes, an honorary vice president of the Sierra Club, stood on a ridgeline high above a patch of former railroad property, breathed reverently and reached out with his hands to embrace the vistas of gleaming ancient lava flows, dry washes pocked with cactus and a lone mountain where a blue bird flitted from smoke tree to creosote bush.

"My god, this landscape is grand," he said. "I'm going to encourage folks to go out and see it, walk it, drive it and photograph it."

Hughes backed Feinstein's ongoing efforts to establish two national monuments on roughly 1 million acres of Mojave Desert that is home for bighorn sheep and desert tortoises, extinct volcanoes and sand dunes.

A year ago, Hughes was among activists who persuaded the Los Angeles Department of Water and Power to drop its plans to build an 85-mile-long "green" power transmission line across desert wilderness preserve and scenic mountains.

Born in 1931, Hughes was raised on a ranch in Whittier when much of the area was wild, and his enduring love affair with wide open spaces began early on. His first memories included trips to Death Valley with his parents. At 13, he had made enough money selling hogs to buy a used car and start exploring California's backcountry.

In 1953, he graduated from Whittier College, where he majored in archaeology, geology and economics.

Hughes later spent nearly a decade working with his father in a wholesale plumbing supply business. After that business was sold, he went on to become a computer executive at Warner Information Systems in Los Angeles.

By the mid-1970s he was a divorced father of three sons and a new member of the Sierra Club and of the Pacific Coast Archaeological Society, leading tours of rivers, caves and remote escarpments decorated with petroglyphs.

Hughes met his second wife, Patty, in 1978 at a Sierra Club meeting. He was elected to the executive committee of the Sierra Club's Angeles Chapter in 1985, and was chapter chairman through 1988. Under his leadership the Sierra Club helped win federal scenic designations for the Tuolumne, Merced and Kings rivers.

"In 1982, our family floated down the Grand Canyon in our own inflatable rafts," recalled Hughes' eldest son, Mark. "In one stretch of rapids, Dad was so determined keep his raft from tipping over that he bent his oar from pulling so hard on it. That was his approach to the things that really mattered."

At the center of his work was the Mojave Desert.

Hughes gave speeches at fundraisers in support of the Bureau of Land Management's ultimately successful effort to save the remote Union Pacific Railroad depot in Kelso, Calif., from demolition.

In the mid-1980s he joined forces with Sierra Club activists Dodson and Judy Sanderson in the fight for the desert protection act. Each brought a special skill to the cause: Dodson dealt with legislation and legal matters; Anderson researched historical documents, maps and property records and Hughes handled the press and public relations.

"Elden was a master at generating a great sound bite on cue: a terse phrase or metaphor that summed up a complex issue in a way anyone could understand," Dodson recalled. "He also knew the desert very well because he'd driven an old blue Ford station wagon of his all over most of it, and walked the rest."

A week ago Hughes received a lifetime achievement award from the Wildlands Conservancy.

"He asked me to scatter his ashes," said David Myers, executive director of the conservancy. "I said, 'Where do you want them scattered, Elden?' He said, 'On the top of Navajo Mountain in Utah.' I said, 'How do you get there?' He smiled and said, 'Rent a boat and go up about 15 miles to Rainbow Bridge. It's about a 10-mile hike in from there.' "

Hughes is survived by his wife, Patty; sons Mark, Paul and Charles, and three grandchildren.

louis.sahagun@latimes.com

Source: http://feeds.latimes.com/~r/latimes/news/science/~3/kaqHAdh99uY/la-me-elden-hughes-20111205,0,2240871.story

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Orphaned children exhibit genetic changes that require nurturing parents

Public release date: 5-Dec-2011
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Contact: Karen N. Peart
karen.peart@yale.edu
203-432-1326
Yale University

Children who experience the stress of separation at birth from biological parents and are brought up in orphanages undergo biological consequences such as changes in their genome functioning, Yale School of Medicine researchers report in a new study.

Published online in the current issue of Development and Psychopathology, the study reports differences in DNA methylation, one of the main regulatory mechanisms of gene expression, or genome functioning. The investigators compared two cohorts: 14 children raised since birth in institutional care and 14 children raised by their biological parents.

Senior author Elena Grigorenko, associate professor at the Yale Child Study Center, and her colleagues took blood samples from children aged 7 to 10 living in orphanages and children growing up in typical families in the northwest region of the Russian Federation. They then profiled the genomes of all the children to identify which biological processes and pathways might be affected by deprivation of parental attention and care.

The team found that in the institutionalized group, there was a greater number of changes in the genetic regulation of the systems controlling immune response and inter-cellular interactions, including a number of important mechanisms in the development and function of the brain.

"Our study shows that the early stress of separation from a biological parent impacts long-term programming of genome function; this might explain why adopted children may be particularly vulnerable to harsh parenting in terms of their physical and mental health," said Grigorenko. "Parenting adopted children might require much more nurturing care to reverse these changes in genome regulation."

###

Other authors on the study included Oksana Naumova, Maria Lee, Roman Koposov, Moshe Szyf, and Mary Dozier.

The study was funded by the Foundation for Child Development, the USA National Institute of Mental Health, and Edna Bennett Pierce.

Citation: Development and Psychopathology: doi:10.1017/S0954579411000605

---

[ | E-mail | Share ]

?

AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Public release date: 5-Dec-2011
[ | E-mail | Share ]

Contact: Karen N. Peart
karen.peart@yale.edu
203-432-1326
Yale University

Children who experience the stress of separation at birth from biological parents and are brought up in orphanages undergo biological consequences such as changes in their genome functioning, Yale School of Medicine researchers report in a new study.

Published online in the current issue of Development and Psychopathology, the study reports differences in DNA methylation, one of the main regulatory mechanisms of gene expression, or genome functioning. The investigators compared two cohorts: 14 children raised since birth in institutional care and 14 children raised by their biological parents.

Senior author Elena Grigorenko, associate professor at the Yale Child Study Center, and her colleagues took blood samples from children aged 7 to 10 living in orphanages and children growing up in typical families in the northwest region of the Russian Federation. They then profiled the genomes of all the children to identify which biological processes and pathways might be affected by deprivation of parental attention and care.

The team found that in the institutionalized group, there was a greater number of changes in the genetic regulation of the systems controlling immune response and inter-cellular interactions, including a number of important mechanisms in the development and function of the brain.

"Our study shows that the early stress of separation from a biological parent impacts long-term programming of genome function; this might explain why adopted children may be particularly vulnerable to harsh parenting in terms of their physical and mental health," said Grigorenko. "Parenting adopted children might require much more nurturing care to reverse these changes in genome regulation."

###

Other authors on the study included Oksana Naumova, Maria Lee, Roman Koposov, Moshe Szyf, and Mary Dozier.

The study was funded by the Foundation for Child Development, the USA National Institute of Mental Health, and Edna Bennett Pierce.

Citation: Development and Psychopathology: doi:10.1017/S0954579411000605

---

[ | E-mail | Share ]

?

AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.

Source: http://www.eurekalert.org/pub_releases/2011-12/yu-oce120511.php

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Ouch! Maggie Q Shows Off 'Nikita' Injuries (omg!)

In The CW's "Nikita," Maggie Q gets herself in and out of dangerous situations, and the actress has sustained a few bumps, bruises - and breaks - on set.

"I had a grate fall on my hand and then I fell down a ladder. It was awful," Maggie told Billy Bush and Kit Hoover on Friday's Access Hollywood Live , showing off her bruised fingers.

PLAY IT NOW: Maggie Q & Shane West On ?Nikita?: There?s ?A Lot More Story To Tell?

Maggie recently got braces off of her first and middle finger, which were hurt recently.

"I broke these two fingers," she said, pointing to her swollen digits.

VIEW THE PHOTOS: Shows & Stars of Fall Television 2011

The actress' ring finger, however, was spared, but she joked she's not close to having someone put a ring on it.

"I'm never gonna get proposed to," she laughed. "That guy has to be crazy."

Joking aside, the stunning beauty revealed she isn't a power player in the game of love.

VIEW THE PHOTOS: The Lovely Ladies Of Primetime Television

"I didn't really date much," she said, telling Billy and Kit her ex count is no more than the fingers on a hand. "I haven't had a lot of relationships."

"Nikita" airs on Fridays at 8 PM ET/PT on The CW.

VIEW THE PHOTOS: The Sexy Ladies Of Sci-Fi

Copyright 2011 by NBC Universal, Inc. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

Source: http://us.rd.yahoo.com/dailynews/rss/entertainment/*http%3A//us.rd.yahoo.com/dailynews/external/omg_rss/rss_omg_en/news_ouch_maggie_q_shows_off_nikita_injuries210735960/43787785/*http%3A//omg.yahoo.com/news/ouch-maggie-q-shows-off-nikita-injuries-210735960.html

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